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Lower Extremity Gait, Mobility and Balance Confidence in Charcot-Marie-Tooth Patients with Cavovarus Foot Deformity

CMT can include problems such as cavovarus foot deformity, footdrop, and sensory changes. These impairments result in altered gait and balance deficits. AFOs are commonly prescribed to individuals with CMT, however there is little accepted guidance on when to prescribe AFOs to people with CMT. Additionally, the biomechanical outcomes of surgical treatment to correct cavovarus foot deformity remain unknown. The comparisons in this study of CMT patients who utilize AFOs to those who have undergone surgery on their feet is an important step toward understanding the of the effects of AFO use and surgical management on the balance and mobility.

About the Study

The aim of this study is to explore the impact ankle-foot orthoses and/or previous foot surgery has on the walking gait, mobility, and balance of individuals with CMT.

Who Can Participate?

Individuals with a genetic or clinical diagnosis of CMT between the ages of 18-70, who live near or are willing to travel to the University of Iowa clinical study site.

Participants must either wear prescription AFOs or have had prior surgery on their feet to correct cavovarus deformity. AFO wearers must be able to walk for short distances without the use of their AFOs.

What is Involved in Participation?

Participants will be asked to undergo gait analysis testing in-person at our human performance lab in North Liberty, IA. This testing involves a completing various walking and balance tasks while wearing reflective sensors and using videography to capture 3D motion analysis. Participants will also answer some brief questionnaires. The total study visit is expected to last 2 hours.

How can people apply to take part? If you are interested in taking part in this research, please contact Lauren Crowe:

Email: lauren-n-crowe@uiowa.edu

Phone: 319-467-7128

Ms. Chrea

Principal Investigator

Bopha Chrea, MD
University of Iowa

CMT Types

  • All

Active

Clinical Study Sites

University of Iowa
Lauren Crowe
701 W. Forevergreen Rd
North Liberty, Iowa, 52317